underscored

@underscored

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Tag:agingClear

Older hearts showed signs of rejuvenation in younger bodies, while younger hearts showed accelerated aging in older ones.

— Packy McCormick
4w ago

I once found his books entertaining—his wild imagination more than compensated for his shortcomings (especially as a prose stylist). But with each passing year, his novels are a little less fun, and a lot more disturbing. But that doesn't diminish their value.

1mo ago

From the middle of life onward, only he remains vitally alive who is ready to die with life. For in the secret hour of life's midday the parabola is reversed, death is born. The second half of life does not signify ascent, unfolding, increase, exuberance, but death, since the end is its goal. The negation of life's fulfillment is synonymous with the refusal to accept its ending. Both mean not wanting to live, and not wanting to live is identical with not wanting to die.

3mo ago

The really frightening thing about middle age is the knowledge that you'll grow out of it.

4mo ago

The work is based on Japanese Nobel Laureate Shinya Yamanaka's eponymous Yakanama Factors, four genes that can rewind any adult cell all the way back to a stem-cell state. The problem is, a reset retina cell forgets it's a retina cell. So Life Bio uses three of the four factors (dropping c-Myc, the one most tied to cancer) and nudges the cells only partway back: younger, but still themselves.

4mo ago

There is only one solution if old age is not to be an absurd parody of our former life, and that is to go on pursuing ends that give our existence a meaning — devotion to individuals, to groups or to causes, social, political, intellectual or creative work… In old age we should wish still to have passions strong enough to prevent us turning in on ourselves. One's life has value so long as one attributes value to the life of others, by means of love, friendship, indignation, compassion.

5mo ago

The therapy didn't help them metabolize alcohol faster. It restored the liver cells' intrinsic ability to withstand stress and regenerate, as if they were young again.

5mo ago

The tissue was just hanging there, loose and slack. My skin had seemingly doubled in size. It was drooping, deflated. I'd never seen anything like it, until I realized I had. It looked like the leg of my grandfather when he was 90 years old.

6mo ago

The difficulty in life is the choice. When you are young, there seems to be so much time and so many choices, none of which seems to matter very much because it seems that later on you can always choose again. But then, suddenly, you are old.

6mo ago

Underscored — save the words that stop you in your tracks.

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