underscored — Underscored

@underscored

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Tag:biotechClear

notboring.co

Most of us will spend 5% of our lives (!) sick from these viruses, they kill 1M people a year, cost $600B annually in productivity, and periodically threaten civilization through pandemics. But respiratory infections are technically challenging and they've been underfunded, so we haven't made much progress against them.
— Nan Ransohoff

2w ago

notboring.co

Weekly Dose of Optimism #197

The work is based on Japanese Nobel Laureate Shinya Yamanaka's eponymous Yakanama Factors, four genes that can rewind any adult cell all the way back to a stem-cell state. The problem is, a reset retina cell forgets it's a retina cell. So Life Bio uses three of the four factors (dropping c-Myc, the one most tied to cancer) and nudges the cells only partway back: younger, but still themselves.

4w ago

notboring.co

Weekly Dose of Optimism #193

Daraxonrasib targets RAS, a cancer-driving protein found in roughly 25% of human cancers and more than 90% of pancreatic cancers, long considered "undruggable." This isn't a cure, but it is a crack, an early sign of the undruggable becoming druggable.

2mo ago

Underscored — save the words that stop you in your tracks.

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