notboring.co

Weekly Dose of Optimism #212

The pharma industry spends enormous effort and money figuring out how to manufacture medicines and get them into people, repeatedly, over and over. If we can safely teach people's own cells to handle more of that manufacturing, we could give people more time living their lives, less time receiving infusions, and ultimately, longer, healthier lives.

whyisthisinteresting

The Monday Media Diet with James McBride

We spend enormous amounts of time listening to people tell us how to get rich, get fit, build companies, and improve our lives. Far fewer people listen to those who have actually lived one. Some of the most valuable lessons I've learned have come from conversations with people in their eighties and nineties.

wired.com

British Space Startup Launches Longevity Lab Into Orbit

The lab will beam back data to train AI models to predict how proteins behind age-related diseases like Alzheimer's and certain cancers behave.

notboring.co

America's Next 250

Two hundred and fifty years seems like a long time, but it's just three peoples' lifetimes at current averages. It would have been six lifetimes back then, except the average American's life expectancy has doubled over the past 250 years.

honest-broker.com

Healing Sounds Are the Medical Miracle of the 21st Century

We think it's completely possible that with enough early imaging in the future, the world could avoid 30% of all deaths and 50% of all healthcare costs.

notboring.co

Weekly Dose of Optimism #197

The work is based on Japanese Nobel Laureate Shinya Yamanaka's eponymous Yakanama Factors, four genes that can rewind any adult cell all the way back to a stem-cell state. The problem is, a reset retina cell forgets it's a retina cell. So Life Bio uses three of the four factors (dropping c-Myc, the one most tied to cancer) and nudges the cells only partway back: younger, but still themselves.

notboring.co

Weekly Dose of Optimism #196

The therapy didn't help them metabolize alcohol faster. It restored the liver cells' intrinsic ability to withstand stress and regenerate, as if they were young again.