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most of the diseases that will claim most of our lives are already addressable with medicines that exist today

Invest Like the Best with Patrick O'Shaughnessy
1w ago
Hidden Brain
The Debt Trap

We like to think that good financial decisions come down to discipline and basic math. But the psychology of money turns out to be deeply complicated.

3w ago

When you're really kind of starving for accurate information uh you know out of out of both sides in terms of what is the condition of the straight of Hormuz uh how is it you know what what is the traffic look like? What is the potential for that to get back online? what is the the knock-on effect going to be for the global economy? all of these, you know, unanswered questions. Um, I think that just makes markets, uh, you know, a little bit more aggressive and volatile when you get any snippet of good news

3w ago

I was a partner at a private equity firm and they used to invest in the education sector. And as I spent time looking at the sector, I really fell in love with the school sector and I looked more closely at the opportunity and my view was how nice would it be to have a group of the best schools around the world that maintain the ethos and values of the schools that are part of the group, but yet share global best practices.

4w ago

The argument in favor of allowing everyday investors to own this stuff is that this stuff has made people really rich over long periods of time and so if you only let rich people own it, they're only going to get richer and the wealth gap explodes.

1mo ago

Probably the most obvious investment in the middle class is investments in infrastructure. Because when people can get to work, when people have more opportunities, when people can spend more time with their families, when people have an absence of stress, when they can take their kids to Disneyland, you know, that's that's accretive to the prosperity of their life.

1mo ago

Unlike most firms chasing power law outcomes, Lead Edge is designed to deliver consistent returns by talking to thousands of companies a year, applying a rigorous eight-point criteria to filter down to a handful of investments, and leveraging a uniquely constructed LP base of world-class executives and entrepreneurs.

1mo ago

We have made a sustained and very deliberate investment over a very long period of time in original independent journalism. That's in journalists, and in the support system structure around them to make sure they can do extraordinary work.

1mo ago

An eight-year-old today doesn't need a driver's license when they're 16. And I think, going back to your point, it's easy to get in these modes where geopolitical white knuckle moment. But if you look, I think ultimately Tesla autonomous is worth a trillion dollars going to a Tesla story.

1mo ago

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